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Chapter 16: The Molecular Basis of Inheritance
 
Pre-Test
 

Pre-Test


1 .       In Griffith's experiments, a harmless variant of S. pneumoniae became pathogenic when mixed with a heat-killed pathogenic variant as a result of _____. (Concept 16.1E-Book) [Hint]

 conjugation
 transduction
 mutation
 natural selection
 transformation
2 .       In the Hershey and Chase experiment that helped confirm that DNA, not protein, was the hereditary material, the key finding was that _____. (Concept 16.1E-Book) [Hint]

 radioactively labeled sulfur was present inside the infected bacteria
 radioactively labeled phosphorus was present inside the infected bacteria
 radioactively labeled carbon was present inside the infected bacteria
 radioactively labeled phosphorus was found outside of the infected bacteria
 radioactively labeled sulfur was found outside of the infected bacteria
3 .       The X-ray diffraction studies conducted by _____ were key to the discovery of the structure of DNA. (Concept 16.1E-Book) [Hint]

 McClintock
 Franklin
 Meselson and Stahl
 Chargaff
 Griffith
4 .       Which of the following is not true of DNA? (Concept 16.1E-Book) [Hint]

 A pairs with C, and G pairs with T.
 Nitrogenous bases are 0.34 nm apart on a DNA strand.
 The double helix is about 2.0 nm wide.
 Its purine bases are larger than its pyrimidine bases.
 One full turn of the helix spans ten bases.
5 .       Who demonstrated that DNA replication is semiconservative? (Concept 16.2E-Book) [Hint]

 Morgan
 Meselson and Stahl
 Chargaff
 Franklin
 Watson and Crick
6 .       Which of the following is not needed for DNA replication? (Concept 16.2E-Book) [Hint]

 ribosomes
 DNA
 nucleotides
 enzymes
 All of the above are needed.
7 .       DNA replication is said to be semiconservative. This means that _____. (Concept 16.2E-Book) [Hint]

 half of the old strand is degraded and half is used as a template for the replication of a new strand
 one of the two resulting double helices is made of two old strands, and the other is made of two new strands
 the old double helix is degraded and half of its nucleotides are used in the construction of two new double helices
 one strand of the new double helix is made of DNA and the other strand is made of RNA
 each new double helix consists of one old and one new strand
8 .       _____ fixes mistakes made during DNA replication; _____ repairs damage to a preexisting double helix. (Concept 16.2E-Book) [Hint]

 Mismatch repair ... nucleotide excision repair
 The leading strand ... the lagging strand
 Operon repair ... histone repair
 Transformation ... transduction
 Proto-oncogene repair ... oncogene
9 .       In nucleotide excision repair, damaged DNA is excised by _____. (Concept 16.2E-Book) [Hint]

 restriction enzymes
 ligase
 primase
 helicase
 nuclease
10 .       The repetitive DNA sequences present at the ends of eukaryotic chromosomes are called _____. (Concept 16.2E-Book) [Hint]

 telomeres
 sarcomeres
 polypeptides
 centromeres
 chromomeres





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